Researchers Found The Effect Of Fatty Acids

Researchers Found The Effect Of Fatty Acids.
Omega-3 fatty acids - nutrients crave hope to be helpful for neurological health - can crucifix the usually impenetrable blood-brain barrier and make their way into the brain, a new study suggests Dec 2013. The decree could have implications for the use of omega-3s as a treatment for diseases such as Alzheimer's, the Swedish researchers said. As published in the Journal of Internal Medicine, scientists at the Karolinska Institute in Stockholm wanted to become proficient how far in the scared system omega-3 fatty acids might travel.

And "Earlier natives studies indicated that omega-3s can protect against Alzheimer's disease, which makes it interesting to think over the effects of dietary supplements containing this group of fatty acids in patients who have already developed the disease," examine lead author Dr Yvonne Freund-Levi said in an institute news release. The researchers said fatty acids stock naturally in the central nervous organized whole of the fetus during gestation, and "it has been assumed that these acids are continually replaced throughout life". But whether this happens - and whether a person's senate makes a difference - has been unknown.

One key question: Do dietary fatty acids have the aptitude to cross the brain's protective blood-brain barrier? This illegitimate barrier shields the brain from harmful chemicals found elsewhere in the body, the researchers said. The outflow is particularly important for Alzheimer's disease research, because prior studies have shown that Alzheimer's patients have lop off levels of a key omega-3 fatty acid in the cerebrospinal fluid (the solution that surrounds the central nervous system). In the six-month study, 18 patients with peaceable Alzheimer's disease got a daily omega-3 supplement while 15 patients received a placebo, or numskull pill.

According to Freund-Levi's group, patients who got the supplement showed higher levels of two big forms of omega-3 fatty acids in their cerebrospinal fluid - docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). The placebo crowd displayed no such change. Concentrations of DHA in cerebrospinal running were directly linked to the degree of change in Alzheimer's disease symptoms and in markers of sore in the fluid.

That's important, the researchers said, because reducing inflammation has been a proposed means of treating Alzheimer's disease. "The discovery suggests that omega-3 fatty acids in dietary supplements hybrid the blood-brain barrier," co-author Jan Palmblad said in the news release.

So "However, much a post remains to be done before we know how these fatty acids can be used in the treatment of Alzheimer's disease to halt reminiscence loss". The study was funded with grants from the Capio Research Foundation, the Dementia Association, the Swedish Alzheimer's Association and Norwegian omega-3 auteur Pronova Biocare A/S, to each others supplements. More information Find out more about omega-3 fatty acids and Alzheimer's disease at the Alzheimer's Association.