Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely hand-me-down diabetes drugs have special effects on men's and women's hearts, a supplementary study suggests. Researchers examined how three commonly prescribed treatments for type 2 diabetes simulated 78 patients who were divided into three groups. One group took metformin alone, the supporter group took metformin plus rosiglitazone (sold under the trade-mark name Avandia) and the third group took metformin plus Lovaza, a type of fish oil. Metformin reduces blood sugar assembly by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin kind-heartedness and moves free fatty acids out of the blood. Lovaza lowers blood levels of another sort of fat called triglycerides. The researchers found that the drugs had very out of the ordinary and sometimes opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders. The lucubrate appears in the December issue of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had arbitrary heart effects in women, it caused the sentiment metabolism of men to burn less sugar and more fats. Chronic burning of fat by the tenderness results in harmful changes that can lead to heart failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making understanding metabolism more normal in men, metformin unaccompanied made it worse, looking even more like a diabetic heart," study elder author Dr Robert Gropler said in a university news release.

And "But in women, metformin had the desired result - lowering fat metabolism and increasing glucose perceptiveness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to reduce some of the negative heart gear of metformin alone in men. Taking rosiglitazone in addition to metformin further improved women's compassion metabolism, compared to taking metformin alone.

The addition of Lovaza to metformin did not have a strong effect either practice for men or women, the researchers said. "Our study suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The bookwork did not, however, substantiate a cause-and-effect link between the drug combinations and nub changes rheumatoid arthritis exacerbation treatment. It showed only an association.