A New Method For Treating Stubborn Hypertension.
A unconventional close to blast away kidney nerves has a striking effect on lowering blood pressure in magnanimity patients whose blood pressure wasn't budging despite trying multiple drugs, Australian researchers report. Although this mug up only followed patients for a short time - six months - the authors feel the approach, which involves delivering radiofrequency energy to the so-called "sympathetic " nerves of the kidney, could have an sense on heart disease and even help lower these patients' endanger of death. The findings were presented Wednesday at the annual meeting of the American Heart Association in Chicago and published simultaneously in The Lancet.
The survey was funded by Ardian, the company that makes the catheter colophon used in the procedure. "This is an extremely important study, and it has the potential for categorically revolutionizing the way we deal with treatment-resistant hypertension," said Dr Suzanne Oparil, director of the Vascular Biology and Hypertension Program at the University of Alabama at Birmingham. Oparil spoke at a dispatch meeting Wednesday to announce the findings, though she was not involved in the study.
Treatment-resistant blood pressure, defined as blood inducement that cannot be controlled on three drugs at full doses, one of which should be a diuretic, afflicts about 15 percent of the hypertensive population. "Many patients are frantic on four or five drugs and have truly refractory hypertension. If it cannot be controlled medically, it carries a expensive cardiovascular risk".
This radioablation procedure had already successfully prevented hypertension in monster models. According to study author Murray Esler, the utensil specifically targets the kidneys' sympathetic nerves. Previous studies have indicated that these nerves are often activated in anthropoid hypertension a cardiologist and scientist at the Baker IDI Heart and Diabetes Institute in Melbourne, Australia.
Tuesday 21 November 2017
Wednesday 15 November 2017
Substances Which Lead To Cancer Growth
Substances Which Lead To Cancer Growth.
A incontestable species of diabetes drug may lower cancer risk in women with type 2 diabetes by up to one-third, while another variety may increase the risk, according to a new study. Cleveland Clinic researchers analyzed observations from more than 25600 women and men with type 2 diabetes to compare how two groups of considerably used diabetes drugs affected cancer risk. The drugs included "insulin sensitizers," which take down blood sugar and insulin levels in the body by increasing the muscle, fat and liver's return to insulin.
The other drugs analyzed were "insulin secretagogues," which lower blood sugar by arousing beta cells in the pancreas to make more insulin. The use of insulin sensitizers in women was associated with a 21 percent decreased cancer gamble compared to insulin secretagogues, the investigators found. Furthermore, the use of a exact insulin sensitizer called thiazolidinedione was associated with a 32 percent decreased cancer hazard in women compared to sulphonylurea, an insulin secretagogue.
A incontestable species of diabetes drug may lower cancer risk in women with type 2 diabetes by up to one-third, while another variety may increase the risk, according to a new study. Cleveland Clinic researchers analyzed observations from more than 25600 women and men with type 2 diabetes to compare how two groups of considerably used diabetes drugs affected cancer risk. The drugs included "insulin sensitizers," which take down blood sugar and insulin levels in the body by increasing the muscle, fat and liver's return to insulin.
The other drugs analyzed were "insulin secretagogues," which lower blood sugar by arousing beta cells in the pancreas to make more insulin. The use of insulin sensitizers in women was associated with a 21 percent decreased cancer gamble compared to insulin secretagogues, the investigators found. Furthermore, the use of a exact insulin sensitizer called thiazolidinedione was associated with a 32 percent decreased cancer hazard in women compared to sulphonylurea, an insulin secretagogue.
Tuesday 14 November 2017
Doctors Have Found A New Way To Treat Intestinal Diseases
Doctors Have Found A New Way To Treat Intestinal Diseases.
Scientists estimate they have found a particular to grow intestinal stem cells and get them to develop into opposite types of mature intestinal cells. This achievement could one day lead to new ways to deal with gastrointestinal disorders such as ulcers or Crohn's disease by replacing a patient's old empty with one that is free of diseases or inflamed tissues, according to researchers at the Massachusetts Institute of Technology and Brigham and Women's Hospital in Boston.
Scientists estimate they have found a particular to grow intestinal stem cells and get them to develop into opposite types of mature intestinal cells. This achievement could one day lead to new ways to deal with gastrointestinal disorders such as ulcers or Crohn's disease by replacing a patient's old empty with one that is free of diseases or inflamed tissues, according to researchers at the Massachusetts Institute of Technology and Brigham and Women's Hospital in Boston.
New Solutions For The Prevention Of Memory Loss From Multiple Sclerosis
New Solutions For The Prevention Of Memory Loss From Multiple Sclerosis.
Being mentally busy may inform reduce memory and learning problems that often befall in people with multiple sclerosis, a new study suggests. It included 44 people, about lifetime 45, who'd had MS for an average of 11 years. Even if they had higher levels of sense damage, those with a mentally active lifestyle had better scores on tests of learning and tribute than those with less intellectually enriching lifestyles. "Many people with MS struggle with learning and memory problems," scrutiny author James Sumowski, of the Kessler Foundation Research Center in West Orange, NJ, said in an American Academy of Neurology telecast release.
So "This study shows that a mentally animated lifestyle might reduce the harmful effects of brain damage on learning and memory. Learning and reminiscence ability remained quite good in people with enriching lifestyles, even if they had a lot of thought damage brain atrophy as shown on brain scans ," Sumowski continued. "In contrast, persons with lesser mentally occupied lifestyles were more likely to suffer learning and memory problems, even at milder levels of knowledge damage".
Sumowski said the "findings suggest that enriching activities may build a person's 'cognitive reserve,' which can be thinking of as a buffer against disease-related memory impairment. Differences in cognitive guardedness among persons with MS may explain why some persons suffer memory problems early in the disease, while others do not begin memory problems until much later, if at all".
The study appears in the June 15 circulation of Neurology. In an editorial accompanying the study, Peter Arnett of Penn State University wrote that "more delve into is needed before any firm recommendations can be made," but that it seemed inexpensive to encourage people with MS to get involved with mentally challenging activities that might improve their cognitive reserve.
What is Multiple Sclerosis? An unpredictable bug of the central nervous system, multiple sclerosis (MS) can pigeon-hole from relatively benign to somewhat disabling to devastating, as communication between the brain and other parts of the body is disrupted. Many investigators accept MS to be an autoimmune disease - one in which the body, through its unaffected system, launches a defensive attack against its own tissues. In the case of MS, it is the nerve-insulating myelin that comes under assault. Such assaults may be linked to an unidentified environmental trigger, conceivably a virus.
Most people experience their first symptoms of MS between the ages of 20 and 40; the commencing symptom of MS is often blurred or double vision, red-green color distortion, or even blindness in one eye. Most MS patients observation muscle weakness in their extremities and difficulty with coordination and balance. These symptoms may be aloof enough to impair walking or even standing. In the worst cases, MS can out partial or complete paralysis.
Being mentally busy may inform reduce memory and learning problems that often befall in people with multiple sclerosis, a new study suggests. It included 44 people, about lifetime 45, who'd had MS for an average of 11 years. Even if they had higher levels of sense damage, those with a mentally active lifestyle had better scores on tests of learning and tribute than those with less intellectually enriching lifestyles. "Many people with MS struggle with learning and memory problems," scrutiny author James Sumowski, of the Kessler Foundation Research Center in West Orange, NJ, said in an American Academy of Neurology telecast release.
So "This study shows that a mentally animated lifestyle might reduce the harmful effects of brain damage on learning and memory. Learning and reminiscence ability remained quite good in people with enriching lifestyles, even if they had a lot of thought damage brain atrophy as shown on brain scans ," Sumowski continued. "In contrast, persons with lesser mentally occupied lifestyles were more likely to suffer learning and memory problems, even at milder levels of knowledge damage".
Sumowski said the "findings suggest that enriching activities may build a person's 'cognitive reserve,' which can be thinking of as a buffer against disease-related memory impairment. Differences in cognitive guardedness among persons with MS may explain why some persons suffer memory problems early in the disease, while others do not begin memory problems until much later, if at all".
The study appears in the June 15 circulation of Neurology. In an editorial accompanying the study, Peter Arnett of Penn State University wrote that "more delve into is needed before any firm recommendations can be made," but that it seemed inexpensive to encourage people with MS to get involved with mentally challenging activities that might improve their cognitive reserve.
What is Multiple Sclerosis? An unpredictable bug of the central nervous system, multiple sclerosis (MS) can pigeon-hole from relatively benign to somewhat disabling to devastating, as communication between the brain and other parts of the body is disrupted. Many investigators accept MS to be an autoimmune disease - one in which the body, through its unaffected system, launches a defensive attack against its own tissues. In the case of MS, it is the nerve-insulating myelin that comes under assault. Such assaults may be linked to an unidentified environmental trigger, conceivably a virus.
Most people experience their first symptoms of MS between the ages of 20 and 40; the commencing symptom of MS is often blurred or double vision, red-green color distortion, or even blindness in one eye. Most MS patients observation muscle weakness in their extremities and difficulty with coordination and balance. These symptoms may be aloof enough to impair walking or even standing. In the worst cases, MS can out partial or complete paralysis.
Thursday 9 November 2017
Mass Screening For Prostate Cancer Can Have Unpleasant Consequences
Mass Screening For Prostate Cancer Can Have Unpleasant Consequences.
Health campaigns that highlight the question of broken-hearted screening rates for prostate cancer to forward such screenings seem to have an unintended effect: They discourage men from undergoing a prostate exam, a budding German study suggests. The finding, reported in the current issue of Psychological Science, stems from till by a research team from the University of Heidelberg that gauged the intention to get screened for prostate cancer to each men over the age of 45 who reside in two German cities.
In earlier research, the learning authors had found that men who had never had such screenings tended to believe that most men hadn't either. In the known effort, the team exposed men who had never been screened to one of two health report statements: either that only 18 percent of German men had been screened in the past year, or that 65 percent of men had been screened.
Health campaigns that highlight the question of broken-hearted screening rates for prostate cancer to forward such screenings seem to have an unintended effect: They discourage men from undergoing a prostate exam, a budding German study suggests. The finding, reported in the current issue of Psychological Science, stems from till by a research team from the University of Heidelberg that gauged the intention to get screened for prostate cancer to each men over the age of 45 who reside in two German cities.
In earlier research, the learning authors had found that men who had never had such screenings tended to believe that most men hadn't either. In the known effort, the team exposed men who had never been screened to one of two health report statements: either that only 18 percent of German men had been screened in the past year, or that 65 percent of men had been screened.
Friday 3 November 2017
Use Of Medicines For Epilepsy During Pregnancy Can Cause A Risk To The Child
Use Of Medicines For Epilepsy During Pregnancy Can Cause A Risk To The Child.
Pregnant women with epilepsy who are taking carbamazepine (Tegretol) to restrain seizures may be at a slight increased hazard of having an infant with spina bifida, a redone study finds. Spina bifida is a condition in which the bones of the spine do not close but the spinal rope remains in place, usually with skin covering the defect. Most children will need lifelong remedying for problems arising from damage to the spinal cord and spinal nerves.
And "For women with epilepsy, seizing control during pregnancy is very important," said lead researcher Lolkje de Jong-van den Berg, from the disunity of pharmacy at the University of Groningen in the Netherlands. "Our learn can help in decisions regarding whether carbamazepine should be the drug of choice in pregnancy". However, the best option with respect to treatment can be chosen only on an individual basis by the woman and her neurologist before pregnancy, weighing the benefits of epilepsy dial against the risk of birth defects, de Jong-van den Berg said.
The circulate is published in the Dec 3, 2010 online edition of the BMJ. For the study, de Jong-van den Berg's tandem reviewed existing research to determine the risk of start defects among women taking Tegretol. The researchers found that infants of women taking Tegretol were 2,6 times more like as not to have spina bifida, compared with women not taking any anti-epileptic medication.
However, the risk associated with Tegretol was less than with another anti-epileptic drug- valproic acid (Depakene). In fact, Tegretol was less chancy than valproic acid when it came to other nativity defects such as hypospadias, where a boy's urinary opening develops in the ill-considered part of the penis or in the scrotum. "Carbamazepine is specifically related to an increased risk of spina bifida," de Jong-van den Berg said. "But you have to nurture in mind that the absolute chance is small".
Pregnant women with epilepsy who are taking carbamazepine (Tegretol) to restrain seizures may be at a slight increased hazard of having an infant with spina bifida, a redone study finds. Spina bifida is a condition in which the bones of the spine do not close but the spinal rope remains in place, usually with skin covering the defect. Most children will need lifelong remedying for problems arising from damage to the spinal cord and spinal nerves.
And "For women with epilepsy, seizing control during pregnancy is very important," said lead researcher Lolkje de Jong-van den Berg, from the disunity of pharmacy at the University of Groningen in the Netherlands. "Our learn can help in decisions regarding whether carbamazepine should be the drug of choice in pregnancy". However, the best option with respect to treatment can be chosen only on an individual basis by the woman and her neurologist before pregnancy, weighing the benefits of epilepsy dial against the risk of birth defects, de Jong-van den Berg said.
The circulate is published in the Dec 3, 2010 online edition of the BMJ. For the study, de Jong-van den Berg's tandem reviewed existing research to determine the risk of start defects among women taking Tegretol. The researchers found that infants of women taking Tegretol were 2,6 times more like as not to have spina bifida, compared with women not taking any anti-epileptic medication.
However, the risk associated with Tegretol was less than with another anti-epileptic drug- valproic acid (Depakene). In fact, Tegretol was less chancy than valproic acid when it came to other nativity defects such as hypospadias, where a boy's urinary opening develops in the ill-considered part of the penis or in the scrotum. "Carbamazepine is specifically related to an increased risk of spina bifida," de Jong-van den Berg said. "But you have to nurture in mind that the absolute chance is small".
Computer Simulation Of The New Look Of The Nose
Computer Simulation Of The New Look Of The Nose.
Computer imaging software gives patients a tolerably beneficial idea of how they'll look after a "nose job," and the lion's share value the preview process, a new study finds. The "morphing" software, worn by plastic surgeons since the 1990s, appears to improve patient-doctor communication, surgeons interested with the study said. "Having an image of an individual in front of you and manipulating that nose on the concealment is better than the patient showing me pictures of 15 other women's noses she likes," said Dr Andrew Frankel, ranking study author and a plastic surgeon at the Lasky Clinic in Beverly Hills, Calif. "It's her phizog and her nose".
Patients who thought their computer image was accurate tended to be happier about the results, the scrutiny found, while plastic surgeons were less likely than patients to think the computer fetish correctly predicted how the remodeled nose turned out. The study is in the November/December discharge of the Archives of Facial Plastic Surgery.
The imaging software was a major step forward in the circle of rhinoplasty, or plastic surgery of the nose. "Before computer imaging, people would bring in pictures of celebrities or other noses they liked and would say, 'Could you place me look like this?'" Frankel said.
But hopeful that was often impossible, plastic surgeons said. Plastic surgeons can break bone, whittle off or reshape the cartilage that makes up the lower two-thirds of the nose, even graft cartilage from other areas of the body onto the nose, but they are still meagre by the nose's basic structure.
And "I have to constantly communicate to the patient what are within reason expectations," said Dr Richard Fleming, a Beverly Hills plastic surgeon. "If someone comes in with a huge Roman nose and they want a little turned up pug nose, you're not thriving to give it to them. It cannot be accomplished".
And even nearly identical noses will look different on different people. "Everything else about the gutsiness structure and the person could be different - the skin color, eyes, level - there is no translation between some Latina celebrity's nose and some Irish 40-year-old's nose".
Computer imaging software gives patients a tolerably beneficial idea of how they'll look after a "nose job," and the lion's share value the preview process, a new study finds. The "morphing" software, worn by plastic surgeons since the 1990s, appears to improve patient-doctor communication, surgeons interested with the study said. "Having an image of an individual in front of you and manipulating that nose on the concealment is better than the patient showing me pictures of 15 other women's noses she likes," said Dr Andrew Frankel, ranking study author and a plastic surgeon at the Lasky Clinic in Beverly Hills, Calif. "It's her phizog and her nose".
Patients who thought their computer image was accurate tended to be happier about the results, the scrutiny found, while plastic surgeons were less likely than patients to think the computer fetish correctly predicted how the remodeled nose turned out. The study is in the November/December discharge of the Archives of Facial Plastic Surgery.
The imaging software was a major step forward in the circle of rhinoplasty, or plastic surgery of the nose. "Before computer imaging, people would bring in pictures of celebrities or other noses they liked and would say, 'Could you place me look like this?'" Frankel said.
But hopeful that was often impossible, plastic surgeons said. Plastic surgeons can break bone, whittle off or reshape the cartilage that makes up the lower two-thirds of the nose, even graft cartilage from other areas of the body onto the nose, but they are still meagre by the nose's basic structure.
And "I have to constantly communicate to the patient what are within reason expectations," said Dr Richard Fleming, a Beverly Hills plastic surgeon. "If someone comes in with a huge Roman nose and they want a little turned up pug nose, you're not thriving to give it to them. It cannot be accomplished".
And even nearly identical noses will look different on different people. "Everything else about the gutsiness structure and the person could be different - the skin color, eyes, level - there is no translation between some Latina celebrity's nose and some Irish 40-year-old's nose".
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