Doctors Recommend A New Type Of Flu Vaccine.
A vaccine that protects children against four strains of flu may be more striking than the usual three-strain vaccine, a renewed cramming suggests. The four-strain (or so-called "quadrivalent") vaccine is available as a nasal sprinkler or an injection for the first time this flu season. The injected version, however, may be in blunt supply, according to the US Centers for Disease Control and Prevention. The study of about 200 children did not measure against the four-strain vaccine to the traditional three-strain vaccine.
Rather, it looked at how kids responded either to the four-strain vaccine or a hepatitis A vaccine, and then compared answer rates for the four-strain flu vaccine to reaction rates for the three-strain vaccine from last year's flu season. "This is the victory large, randomized, controlled trial to demonstrate the efficacy of a quadrivalent flu vaccine against influenza in children," said look at co-author Dr Ghassan Dbaibo.
"The results showed that, by preventing middle to severe influenza, vaccination achieved reductions of 61 percent to 77 percent in doctors' visits, hospitalizations, absences from drill and parental absences from work," said Dbaibo, at the sphere of pediatrics and adolescent medicine at the American University of Beirut Medical Center, in Lebanon. The results authenticate the effectiveness of the vaccine against influenza, and particularly against moderate to tough influenza.
"They also showed an 80 percent reduction in lower respiratory tract infections, which is the most common important outcome of influenza. Therefore, vaccination of children in this age group can help to reduce the significant gravamen placed on parents, doctors and hospitals every flu season. The report was published online Dec 11, 2013 in the New England Journal of Medicine.
The look was funded by GlaxoSmithKline, maker of the four-strain vaccine hand-me-down in the study. Dr Lisa Grohskopf, a medical constable in CDC's influenza division, said there are several flu vaccine options for children. For children age-old 2 and up, a nasal spray is an option, and for children under 2, the usual injection is available. "The nasal spread vaccine is a quadrivalent vaccine, which has four different flu viruses in it.
Showing posts with label strain. Show all posts
Showing posts with label strain. Show all posts
Monday 25 March 2019
Friday 30 June 2017
Excessive Use Of Antibiotics In Animal Husbandry Creates A Deadly Intestinal Bacteria
Excessive Use Of Antibiotics In Animal Husbandry Creates A Deadly Intestinal Bacteria.
The theme of E coli bacteria that this month killed dozens of rank and file in Europe and sickened thousands more may be more harmful because of the way it has evolved, a new review suggests. Scientists say this strain of E coli produces a particularly noxious toxin and also has a good ability to hold on to cells within the intestine. This, alongside the fact that it is also resistant to many antibiotics, has made the soi-disant O104:H4 strain both deadlier and easier to transmit, German researchers report.
And "This exertion of E coli is much nastier than its more common cousin E coli O157, which is unclean enough - about three times more virulent," said Hugh Pennington, emeritus professor of bacteriology at the University of Aberdeen in Scotland and writer of an accompanying editorial published online June 23, 2011 in The Lancet Infectious Diseases. Another study, published the same date in the New England Journal of Medicine, concludes that, as of June 18, 2011, more than 3200 clan have fallen hostile in Germany due to the outbreak, including 39 deaths.
In fact, the German extraction - traced to sprouts raised at a German organic farm - "was reliable for the deadliest E coli outbreak in history. It may well be so nasty because it combines the virulence factors of shiga toxin, produced by E coli O157, and the structure for sticking to intestinal cells cast-off by another strain of E coli, enteroaggregative E coli, which is known to be an important cause of diarrhea in poorer countries".
Shiga toxin can also daily spur what doctors call "hemolytic uremic syndrome," a potentially devastating form of kidney failure. In the New England Journal of Medicine study, German researchers estimate that 25 percent of outbreak cases involved this complication. The bottom line, according to Pennington: "E coli hasn't gone away. It still springs surprises".
To distinguish out how this thread of the intestinal bug proved so lethal, researchers led by Dr Helge Karch from the University of Munster wilful 80 samples of the bacteria from affected patients. They tested the samples for shiga toxin-producing E coli and also for acerbity genes of other types of E coli.
The theme of E coli bacteria that this month killed dozens of rank and file in Europe and sickened thousands more may be more harmful because of the way it has evolved, a new review suggests. Scientists say this strain of E coli produces a particularly noxious toxin and also has a good ability to hold on to cells within the intestine. This, alongside the fact that it is also resistant to many antibiotics, has made the soi-disant O104:H4 strain both deadlier and easier to transmit, German researchers report.
And "This exertion of E coli is much nastier than its more common cousin E coli O157, which is unclean enough - about three times more virulent," said Hugh Pennington, emeritus professor of bacteriology at the University of Aberdeen in Scotland and writer of an accompanying editorial published online June 23, 2011 in The Lancet Infectious Diseases. Another study, published the same date in the New England Journal of Medicine, concludes that, as of June 18, 2011, more than 3200 clan have fallen hostile in Germany due to the outbreak, including 39 deaths.
In fact, the German extraction - traced to sprouts raised at a German organic farm - "was reliable for the deadliest E coli outbreak in history. It may well be so nasty because it combines the virulence factors of shiga toxin, produced by E coli O157, and the structure for sticking to intestinal cells cast-off by another strain of E coli, enteroaggregative E coli, which is known to be an important cause of diarrhea in poorer countries".
Shiga toxin can also daily spur what doctors call "hemolytic uremic syndrome," a potentially devastating form of kidney failure. In the New England Journal of Medicine study, German researchers estimate that 25 percent of outbreak cases involved this complication. The bottom line, according to Pennington: "E coli hasn't gone away. It still springs surprises".
To distinguish out how this thread of the intestinal bug proved so lethal, researchers led by Dr Helge Karch from the University of Munster wilful 80 samples of the bacteria from affected patients. They tested the samples for shiga toxin-producing E coli and also for acerbity genes of other types of E coli.
Sunday 12 March 2017
Fatal Case Of Black Plague In The USA
Fatal Case Of Black Plague In The USA.
In 2009, a 60-year-old American lab researcher was mysteriously, and fatally, infected with the awful anguish while conducting experiments using a weakened, non-virulent overburden of the microbe. Now, a follow-up investigation has confirmed that the researcher died because of a genetic predisposition that made him exposed to the hazards of such bacterial contact. The reborn report appears to set aside fears that the strain of plague in question (known by its painstaking name as "Yersinia pestis") had unpredictably mutated into a more lethal one that might have circumvented standard research lab insurance measures.
And "This was a very isolated incident," said study co-author Dr Karen Frank, superintendent of clinical microbiology and immunology laboratories in the department of pathology at the University of Chicago Medical Center. "But the outstanding point is that all levels of public health were mobilized to probe this case as soon as it occurred. "And what we now know is that, despite concerns that we might have had a non-virulent strain of virus that unexpectedly modified and became virulent, that is not what happened.
This was an precedent of a person with a specific genetic condition that caused him to be uniquely susceptible to infection. And what that means is that the precautions that are typically taken for handling this type of a-virulent spirit in a lab setting are safe and sufficient". Frank and her UC colleague, Dr Olaf Schneewind, reported on the instance in the June 30 issue of the New England Journal of Medicine.
According to the National Institutes of Health, prairie dogs, rats and other rodents, and the fleas that morsel them, are the rule carriers of the bacteria responsible for the spread of the deadly plague, and they can infect people through bites. In the 1300s, the soi-disant "Black Death" claimed the lives of more than 30 million Europeans (about one-third of the continent's aggregate population at the time). In the 1800s, 12 million Chinese died from the illness.
Today, only 10 to 20 Americans are infected yearly. As beginning reported by the US Centers for Disease Control and Prevention on Feb 25, 2011, the crate of the American lab researcher began in September 2009, when he sought heed at a hospital exigency room following several days of breathing difficulties, dry coughing, fevers, chills, and weakness. Thirteen hours after admission, he was dead.
In 2009, a 60-year-old American lab researcher was mysteriously, and fatally, infected with the awful anguish while conducting experiments using a weakened, non-virulent overburden of the microbe. Now, a follow-up investigation has confirmed that the researcher died because of a genetic predisposition that made him exposed to the hazards of such bacterial contact. The reborn report appears to set aside fears that the strain of plague in question (known by its painstaking name as "Yersinia pestis") had unpredictably mutated into a more lethal one that might have circumvented standard research lab insurance measures.
And "This was a very isolated incident," said study co-author Dr Karen Frank, superintendent of clinical microbiology and immunology laboratories in the department of pathology at the University of Chicago Medical Center. "But the outstanding point is that all levels of public health were mobilized to probe this case as soon as it occurred. "And what we now know is that, despite concerns that we might have had a non-virulent strain of virus that unexpectedly modified and became virulent, that is not what happened.
This was an precedent of a person with a specific genetic condition that caused him to be uniquely susceptible to infection. And what that means is that the precautions that are typically taken for handling this type of a-virulent spirit in a lab setting are safe and sufficient". Frank and her UC colleague, Dr Olaf Schneewind, reported on the instance in the June 30 issue of the New England Journal of Medicine.
According to the National Institutes of Health, prairie dogs, rats and other rodents, and the fleas that morsel them, are the rule carriers of the bacteria responsible for the spread of the deadly plague, and they can infect people through bites. In the 1300s, the soi-disant "Black Death" claimed the lives of more than 30 million Europeans (about one-third of the continent's aggregate population at the time). In the 1800s, 12 million Chinese died from the illness.
Today, only 10 to 20 Americans are infected yearly. As beginning reported by the US Centers for Disease Control and Prevention on Feb 25, 2011, the crate of the American lab researcher began in September 2009, when he sought heed at a hospital exigency room following several days of breathing difficulties, dry coughing, fevers, chills, and weakness. Thirteen hours after admission, he was dead.
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