Scientists Have Found A New Method Of Cancer Treatment.
Blocking a main protein complicated in the growth of a rare, incurable type of soft-tissue cancer may ice the disease, according to a new study involving mice. Researchers from UT Southwestern found that inhibiting the power of a protein, known as BRD4, caused cancer cells in malignant peripheral impudence sheath tumors to die. Malignant peripheral nerve sheath tumors are highly assertive soft-tissue cancers, or sarcomas, that form around nerves.
And "This study identifies a potential unfledged therapeutic target to combat malignant peripheral nerve sheath tumor, an incurable genre of cancer that is typically fatal," study senior author Dr Lu Le, an deputy professor of dermatology, said in a university news release. "The findings also provide leading insight into what causes these tumors to develop". The findings were published online Dec 26, 2013 in the daily Cell Reports.
Although malignant peripheral nerve sheath tumors can amplify randomly, about 50 percent of cases involve patients with a genetic disorder called neurofibromatosis category 1. This disorder affects one in 3500 people. About 10 percent of those patients will go on to reveal the soft-tissue cancer, according to the news release. For the study, the researchers examined changes in cells as they evolved into cancerous soft-tissue tumors.