Both Medications And Deep Brain Stimulation Surgery May Make Better Life With Parkinson'S Disease.
Parkinson's disorder patients do better if they stand engaged brain stimulation surgery in addition to treatment with medication, new research suggests. One year after having the procedure, patients who underwent the surgery reported better rank of life and improved capability to get around and engage in routine daily activities compared to those who were treated with medication alone, according to the enquiry published in the April 29 online edition of The Lancet Neurology.
The study authors distinguished that while the surgery can provide significant benefits for patients, there also is a risk of serious complications. In astute brain stimulation, electrical impulses are sent into the brain to adjust areas that control movement, according to history information in a news release about the research. In the new study, Dr Adrian Williams of Queen Elizabeth Hospital in Birmingham and colleagues in the United Kingdom randomly assigned 366 Parkinson's malady patients to either away with drug treatment or drug treatment gain surgery.
One year later, the patients took surveys about how well they were doing. "Surgery is likely to last an important treatment option for patients with Parkinson's disease, especially if the way in which deep brain stimulation exerts its remedial benefits is better understood, if its use can be optimized by better electrode placement and settings, and if patients who would have the greatest gain can be better identified," the authors concluded.
Deep brain stimulation (DBS) is a surgical procedure hand-me-down to treat a variety of disabling neurological symptoms—most commonly the debilitating symptoms of Parkinson's c murrain (PD), such as tremor, rigidity, stiffness, slowed movement, and walking problems. The tradition is also used to treat essential tremor, a common neurological movement disorder.
Showing posts with label stimulation. Show all posts
Showing posts with label stimulation. Show all posts
Friday, 8 March 2019
Wednesday, 13 February 2019
Excess Weight Is Not The Verdict
Excess Weight Is Not The Verdict.
For the senior time, researchers have shown that implanting electrodes in the brain's "feeding center" can be safely done - in a tender to lay open a new treatment option for severely obese people who fail to shed pounds even after weight-loss surgery. In a beginning study with three patients, researchers in June 2013 found that they could safely use the therapy, known as acute brain stimulation (DBS). Over almost three years, none of the patients had any important side effects, and two even lost some weight - but it was temporary. "The sooner thing we needed to do was to see if this is safe," said lead researcher Dr Donald Whiting, depravity chairman of neurosurgery at Allegheny General Hospital in Pittsburgh.
And "We're at the point now where it looks groove on it is". The study, reported in the Journal of Neurosurgery and at a meeting this week of the International Neuromodulation Society in Berlin, Germany, was not meant to examine effectiveness. So the big remaining subject is, can deep brain stimulation actually promote lasting weight loss?
"Nobody should get the end that this has been shown to be effective. This is not something you can go ask your doctor about". Right now, deep wit stimulation is sometimes used for tough-to-treat cases of Parkinson's disease, a movement disorder that causes tremors, howling muscles, and balance and coordination problems. A surgeon implants electrodes into delineated movement-related areas of the brain, then attaches those electrodes to a neurostimulator placed under the skin near the collarbone.
The neurostimulator continually sends infinitesimal electrical pulses to the brain, which in turn interferes with the perverse activity that causes tremors and other symptoms. What does that have to do with obesity? In theory deep planner stimulation might be able to "override" brain signaling involved in eating, metabolism or feelings of fullness.
Research in animals has shown that electrical stimulation of a thorough area of the brain - the lateral hypothalamic area - can drive weight loss even if calorie intake stays the same. The new consider marks the first time that deep brain stimulation has been tried in that brain region. And it's an high-level first step to show that not only could these three severely obese people get through the surgery, but they also seemed to have no not joking effects from the brain stimulation, said Dr Casey Halpern, a neurosurgeon at the University of Pennsylvania who was not interested in the research.
For the senior time, researchers have shown that implanting electrodes in the brain's "feeding center" can be safely done - in a tender to lay open a new treatment option for severely obese people who fail to shed pounds even after weight-loss surgery. In a beginning study with three patients, researchers in June 2013 found that they could safely use the therapy, known as acute brain stimulation (DBS). Over almost three years, none of the patients had any important side effects, and two even lost some weight - but it was temporary. "The sooner thing we needed to do was to see if this is safe," said lead researcher Dr Donald Whiting, depravity chairman of neurosurgery at Allegheny General Hospital in Pittsburgh.
And "We're at the point now where it looks groove on it is". The study, reported in the Journal of Neurosurgery and at a meeting this week of the International Neuromodulation Society in Berlin, Germany, was not meant to examine effectiveness. So the big remaining subject is, can deep brain stimulation actually promote lasting weight loss?
"Nobody should get the end that this has been shown to be effective. This is not something you can go ask your doctor about". Right now, deep wit stimulation is sometimes used for tough-to-treat cases of Parkinson's disease, a movement disorder that causes tremors, howling muscles, and balance and coordination problems. A surgeon implants electrodes into delineated movement-related areas of the brain, then attaches those electrodes to a neurostimulator placed under the skin near the collarbone.
The neurostimulator continually sends infinitesimal electrical pulses to the brain, which in turn interferes with the perverse activity that causes tremors and other symptoms. What does that have to do with obesity? In theory deep planner stimulation might be able to "override" brain signaling involved in eating, metabolism or feelings of fullness.
Research in animals has shown that electrical stimulation of a thorough area of the brain - the lateral hypothalamic area - can drive weight loss even if calorie intake stays the same. The new consider marks the first time that deep brain stimulation has been tried in that brain region. And it's an high-level first step to show that not only could these three severely obese people get through the surgery, but they also seemed to have no not joking effects from the brain stimulation, said Dr Casey Halpern, a neurosurgeon at the University of Pennsylvania who was not interested in the research.
Tuesday, 15 January 2019
Doctors Recommend Carefully Treat Tinnitus
Doctors Recommend Carefully Treat Tinnitus.
Patients trial from the intense, continuing and sometimes untreatable ringing in the ear known as tinnitus may get some relief from a new combination therapy, overture research suggests. The study looked at treatment with daily targeted electrical stimulation of the body's skittish system paired with sound therapy. Half of the procedure - "vagus spirit stimulation" - centers on direct stimulation of the vagus nerve, one of 12 cranial nerves that winds its trail through the abdomen, lungs, heart and brain stem.
Patients are also exposed to "tone therapy" - carefully selected tones that perjure outside the frequency file of the troubling ear-ringing condition. Indications of the new treatment's success, however, are so far based on a very mignon pool of patients, and relief was not universal. "Half of the participants demonstrated large decreases in their tinnitus symptoms, with three of them showing a 44 percent reduction in the burden of tinnitus on their daily lives," said den co-author Sven Vanneste.
But, "five participants, all of whom were on medications for other problems, did not show significant changes". For those participants, pharmaceutical interactions might have blocked the therapy's impact, Vanneste suggested. "However, further delving needs to be conducted to confirm this," said Vanneste, an associate professor at the School of Behavioral and Brain Sciences at the University of Texas at Dallas. The study, conducted in collaboration with researchers at the University Hospital Antwerp, in Belgium, appeared in a current matter of the journal Neuromodulation: Technology at the Neural Interface.
The authors disclosed that two members of the over team have a run connection with MicroTransponder Inc, the manufacturer of the neurostimulation software used to deliver vagus chutzpah stimulation therapy. One researcher is a MicroTransponder employee, the other a consultant. Vanneste himself has no connection with the company.
According to the US National Institute on Deafness and Other Communication Disorders, nearly 23 million American adults have at some pith struggled with consideration ringing for periods extending beyond three months. Yet tinnitus is not considered to be a complaint in itself, but rather an indication of trouble somewhere along the auditory nerve pathway. Noise-sparked hearing breakdown can set off ringing, as can ear/sinus infection, brain tumors, heart disease, hormonal imbalances, thyroid problems and medical complications.
A numbers of treatments are available. The two most conspicuous are "cognitive behavioral therapy" (to promote relaxation and mindfulness) and "tinnitus retraining therapy" (to essentially pretence the ringing with more neutral sounds). In 2012, a Dutch tandem investigated a combination of both approaches, and found that the combined therapy process did seem to reduce reduction and improve patients' quality of life better than either intervention alone.
Patients trial from the intense, continuing and sometimes untreatable ringing in the ear known as tinnitus may get some relief from a new combination therapy, overture research suggests. The study looked at treatment with daily targeted electrical stimulation of the body's skittish system paired with sound therapy. Half of the procedure - "vagus spirit stimulation" - centers on direct stimulation of the vagus nerve, one of 12 cranial nerves that winds its trail through the abdomen, lungs, heart and brain stem.
Patients are also exposed to "tone therapy" - carefully selected tones that perjure outside the frequency file of the troubling ear-ringing condition. Indications of the new treatment's success, however, are so far based on a very mignon pool of patients, and relief was not universal. "Half of the participants demonstrated large decreases in their tinnitus symptoms, with three of them showing a 44 percent reduction in the burden of tinnitus on their daily lives," said den co-author Sven Vanneste.
But, "five participants, all of whom were on medications for other problems, did not show significant changes". For those participants, pharmaceutical interactions might have blocked the therapy's impact, Vanneste suggested. "However, further delving needs to be conducted to confirm this," said Vanneste, an associate professor at the School of Behavioral and Brain Sciences at the University of Texas at Dallas. The study, conducted in collaboration with researchers at the University Hospital Antwerp, in Belgium, appeared in a current matter of the journal Neuromodulation: Technology at the Neural Interface.
The authors disclosed that two members of the over team have a run connection with MicroTransponder Inc, the manufacturer of the neurostimulation software used to deliver vagus chutzpah stimulation therapy. One researcher is a MicroTransponder employee, the other a consultant. Vanneste himself has no connection with the company.
According to the US National Institute on Deafness and Other Communication Disorders, nearly 23 million American adults have at some pith struggled with consideration ringing for periods extending beyond three months. Yet tinnitus is not considered to be a complaint in itself, but rather an indication of trouble somewhere along the auditory nerve pathway. Noise-sparked hearing breakdown can set off ringing, as can ear/sinus infection, brain tumors, heart disease, hormonal imbalances, thyroid problems and medical complications.
A numbers of treatments are available. The two most conspicuous are "cognitive behavioral therapy" (to promote relaxation and mindfulness) and "tinnitus retraining therapy" (to essentially pretence the ringing with more neutral sounds). In 2012, a Dutch tandem investigated a combination of both approaches, and found that the combined therapy process did seem to reduce reduction and improve patients' quality of life better than either intervention alone.
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