New Methods Of Treatment Of Autoimmune Diseases.
A imaginative remedy for multiple sclerosis that teaches the body to recognize and then ignore its own nerve tissue appears to be non-poisonous and well-tolerated in humans, a small new study shows in June 2013. If larger studies authenticate the technique can slow or stop the disease, the therapy would be a completely untrained way to treat autoimmune diseases such as multiple sclerosis (MS) and type 1 diabetes. Most treatments for MS and other autoimmune diseases labour by broadly suppressing immune function, leaving patients helpless to infections and cancers.
The new treatment targets only the proteins that come under incursion when the immune system fails to recognize them as a normal part of the body. By creating open-mindedness to only a select few proteins, researchers hope they will be able to cure the disease but leave the rest of the body's defenses on guard. "This is superior work," said Dr Lawrence Steinman, a professor of neurology at Stanford University who was not active with the study.
And "Very few investigators are trying therapies in humans aimed at only turning off unwanted immune responses and leaving the rest of the immune system complete to fight infections - to do surveillance against cancer. The early results show encouragement". For the study, published in the June 5, 2013 appear of the journal Science Translational Medicine, researchers in the United States and Germany recruited nine patients with MS.
Seven had the relapsing-remitting make of the disease, while two others had supporting progressive MS (a more advanced phase). All were between the ages of 18 and 55, and were in edible health except for their MS. Blood tests conducted before the treatments showed that each tireless had an immune reaction against at least one of seven myelin proteins.
Myelin is a white chain made of fats and proteins that wraps nerve fibers, allowing them to conduct electrical signals through the body. In MS, the body attacks and drop by drop destroys these myelin sheaths. The injury disrupts nerve signals and leads to myriad symptoms, including numbness, tingling, weakness, diminution of balance and disrupted muscle coordination.
Six patients in the study had low disease activity, while three others had a days of more active disease. Most were not experiencing symptoms at the time of their treatment. On the time of the treatments, patients spent about two hours hooked up to a machine that filtered their blood, harvesting chalk-white cells while returning red cells and plasma to the body.
Showing posts with label proteins. Show all posts
Showing posts with label proteins. Show all posts
Saturday, 12 May 2018
Saturday, 5 May 2018
Scientists Have Discovered A New Appointment DNA
Scientists Have Discovered A New Appointment DNA.
Another lex non scripta 'common law within DNA has been discovered by scientists - a pronouncement that the researchers say sheds light on how changes to DNA trouble health. Since the genetic code was first deciphered in the 1960s, scientists have believed it was employed solely to write information about proteins. But this new study from University of Washington scientists found that genomes use the genetic cryptogram to write two separate languages.
One wording describes how proteins are made, and the other helps direct genetic activity in cells. One patois is written on top of the other, which is why this other language went undiscovered for so long, according to the report in the Dec 13, 2013 end of Science. "For over 40 years, we have assumed that DNA changes affecting the genetic organization solely impact how proteins are made," team leader Dr John Stamatoyannopoulos, an associate professor of genome sciences and of medicine, said in a university news release.
Another lex non scripta 'common law within DNA has been discovered by scientists - a pronouncement that the researchers say sheds light on how changes to DNA trouble health. Since the genetic code was first deciphered in the 1960s, scientists have believed it was employed solely to write information about proteins. But this new study from University of Washington scientists found that genomes use the genetic cryptogram to write two separate languages.
One wording describes how proteins are made, and the other helps direct genetic activity in cells. One patois is written on top of the other, which is why this other language went undiscovered for so long, according to the report in the Dec 13, 2013 end of Science. "For over 40 years, we have assumed that DNA changes affecting the genetic organization solely impact how proteins are made," team leader Dr John Stamatoyannopoulos, an associate professor of genome sciences and of medicine, said in a university news release.
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