Some Antiepileptic Drugs During Pregnancy Can Have A Negative Impact On The Development Of The CNS Of The Teens

Some Antiepileptic Drugs During Pregnancy Can Have A Negative Impact On The Development Of The CNS Of The Teens.
Teens born to women who took two or more epilepsy drugs while abounding fared worse in ready than peers with no prenatal location to those medications, a huge Swedish study has found. Also, teens born to epileptic mothers in regular tended to score lower in several subjects, including math and English. The findings confirm earlier research that linked prenatal disclosing to epilepsy drugs, particularly valproic acid (brand names include Depakene and Depakote), to adversative effects on a child's ability to process information, solve problems and make decisions.

And "Our results suggest that contact to several anti-epileptic drugs in utero may have a negative effect on a child's neurodevelopment," said analyse author Dr Lisa Forsberg of Karolinska University Hospital. The memorize was published online Nov 4, 2010 in Epilepsia.

The study was retrospective, sense that it looked backwards in time. Using national medical records and a study conducted by a specific hospital, Forsberg and her team identified women with epilepsy who gave birth between 1973 and 1986, as well as those who worn anti-epileptic drugs during pregnancy. The team then obtained records of children's school conduct from a registry that provides grades for all students leaving school at 16, the age that mandatory drilling ends in Sweden.

The researchers identified 1,235 children born to epileptic mothers. Of those, 641 children were exposed to one anti-epileptic treat and 429 to two or more; 165 children had no known divulging to the medications. The researchers then compared those children's school completion to that of all other children born in Sweden (more than 1,3 million) during that 13-year period.

The teens exposed to more than one anti-epileptic deaden in the womb were less likely to get a final grade than those in the general population, said Forsberg. Not receiving a end grade generally means not attending general school because of mental deficits.