New Methods Of Treatment Of Ovarian Cancer.
Women with advanced ovarian cancer who net hysterical chemotherapy directly into their stomach area may live at least one year longer than women who take standard intravenous chemotherapy, a new study says. But this survival acrimony may come at the expense of more side effects. "The long-term benefits are cute significant," said study author Dr Devansu Tewari, director of gynecologic oncology at the Southern California Permanente Medical Group, in Orange County. "There is no lessons of ovarian cancer treatments that has shown a greater survival advantage".
Intraperitoneal chemotherapy involves bathing the abdominal limit with chemotherapy agents. By contrast, intravenous (IV) chemotherapy is delivered throughout the body via the bloodstream. The US National Cancer Institute currently recommends intraperitoneal remedial programme for women with ovarian cancer who have had in the money surgery to carry away the tumor.
The 10-year follow-up data from two studies of nearly 900 women with advanced ovarian cancer will be presented Saturday at the annual convocation of the Society of Gynecologic Oncology, in Los Angeles. In 2013, more than 22000 American women will be diagnosed with ovarian cancer, and more than 14000 will perish from the disease, according to the US National Cancer Institute. There are no original screening tests for ovarian cancer, which is why it is often diagnosed when the cancer has already throw freelance of the ovaries.
For this reason, survival rates tend to be very low. In the new study, women who received the intraperitoneal healing were 17 percent more likely to survive longer than those who got IV chemotherapy. On average, women in the intraperitoneal party survived for more than five years, while those who received IV chemotherapy survived for about four years, the reflect on found. But survival benefits aside, intraperitoneal chemotherapy does take counsel a greater risk of side effects - such as abdominal spasm and numbness in the hands and feet - and not all women can tolerate this high concentration of cancer-killing drugs.
The drugs are also engaged more slowly, providing more exposure to the medicine. The same properties that make the intraperitoneal psychoanalysis more effective likely play a role in causing more side effects, the researchers said. In general, six cycles of intraperitoneal chemotherapy are recommended, and can be given in inpatient or outpatient settings. The more cycles the women completed, the greater their survival advantage, the exploration showed.