Binge-Eating Disorder And Attention Deficit Hyperactivity Disorder.
A downer reach-me-down to treat attention-deficit/hyperactivity disorder (ADHD) may also help treat binge-eating disorder, introductory research suggests. At higher doses tested, the prescription drug Vyvanse curtailed the overdone food consumption that characterizes binge-eating disorder. Vyvanse (lisdexamfetamine dimesylate) is solely approved in the United States to study ADHD, and no drug has been approved to curb binge-eating disorder. Binge-eating - only recently recognized by the psychiatric community as a plain disorder - is characterized by reoccurring episodes of excessive food consumption accompanied by a sense of loss of control and unconscious distress, the study authors noted.
It is also associated with obesity. "Right now the most commonly used medications are epilepsy drugs," said look co-author Dr James Mitchell, president of the Neuropsychiatric Research Institute in Fargo, ND. "And they do employee patients to eat well and cut down on weight. However, their aspect effect profiles are not great, with their impact on cognitive mental impairment in itemized making them difficult for many patients to tolerate".
What Mitchell found most impressive in the new study on Vyvanse was the drug's effectiveness and that it was "very well tolerated". The 14-week study, reported in the Jan 14, 2015 online copy of JAMA Psychiatry, was funded by Shire Development, LLC, the fabricator of Vyvanse. The researchers tracked outcomes middle roughly 260 patients with moderate to strict binge-eating disorder between 2011 and 2012. All of the participants were between 18 and 55 years old, and none had a diagnosis of any additional psychiatric disorders, such as ADHD, anorexia or bulimia.
The volunteers were divided into four groups for 11 weeks. The original faction received 30 milligrams (mg) of Vyvanse daily, while the aid and third groups started with 30 mg a day, increasing to 50 mg or 70 mg (respectively) within three weeks. A fourth gathering took an listless placebo pill. Vyvanse did not appear to help curtail binge eating at the lowest dosage. But population taking the higher doses experienced a bigger drop in the number of days they binged each week compared with the placebo group, the researchers found.
Showing posts with label disorder. Show all posts
Showing posts with label disorder. Show all posts
Sunday 30 June 2019
Saturday 25 May 2019
Post-Traumatic Stress Disorder And Type 2 Diabetes
Post-Traumatic Stress Disorder And Type 2 Diabetes.
Women with post-traumatic ictus fight seem more likely than others to develop type 2 diabetes, with severe PTSD almost doubling the risk, a further study suggests. The research "brings to attention an unrecognized problem," said Dr Alexander Neumeister, manager of the molecular imaging program for angst and mood disorders at New York University School of Medicine. It's crucial to deal with both PTSD and diabetes when they're interconnected in women. Otherwise, "you can try to treat diabetes as much as you want, but you'll never be fully successful".
PTSD is an desire disorder that develops after living through or witnessing a perilous event. People with the disorder may feel intense stress, suffer from flashbacks or experience a "fight or flight" reply when there's no apparent danger. It's estimated that one in 10 US women will promote PTSD in their lifetime, with potentially severe effects, according to the study. "In the past few years, there has been an increasing prominence to PTSD as not only a mental disorder but one that also has very profound effects on brain and body function who wasn't confusing in the new study.
Among other things, PTSD sufferers gain more weight and have an increased imperil of cardiac disease compared to other people. The new study followed 49,739 female nurses from 1989 to 2008 - old 24 to 42 at the beginning - and tracked weight, smoking, peril to trauma, PTSD symptoms and type 2 diabetes. People with type 2 diabetes have higher than customary blood sugar levels. Untreated, the disease can cause serious problems such as blindness or kidney damage.
Women with post-traumatic ictus fight seem more likely than others to develop type 2 diabetes, with severe PTSD almost doubling the risk, a further study suggests. The research "brings to attention an unrecognized problem," said Dr Alexander Neumeister, manager of the molecular imaging program for angst and mood disorders at New York University School of Medicine. It's crucial to deal with both PTSD and diabetes when they're interconnected in women. Otherwise, "you can try to treat diabetes as much as you want, but you'll never be fully successful".
PTSD is an desire disorder that develops after living through or witnessing a perilous event. People with the disorder may feel intense stress, suffer from flashbacks or experience a "fight or flight" reply when there's no apparent danger. It's estimated that one in 10 US women will promote PTSD in their lifetime, with potentially severe effects, according to the study. "In the past few years, there has been an increasing prominence to PTSD as not only a mental disorder but one that also has very profound effects on brain and body function who wasn't confusing in the new study.
Among other things, PTSD sufferers gain more weight and have an increased imperil of cardiac disease compared to other people. The new study followed 49,739 female nurses from 1989 to 2008 - old 24 to 42 at the beginning - and tracked weight, smoking, peril to trauma, PTSD symptoms and type 2 diabetes. People with type 2 diabetes have higher than customary blood sugar levels. Untreated, the disease can cause serious problems such as blindness or kidney damage.
Friday 18 January 2019
Autism Is Not Associated With Childhood Infections
Autism Is Not Associated With Childhood Infections.
Infections during beginning or girlhood do not seem to raise the risk of autism, new research finds. Researchers analyzed start records for the 1,4 million children born in Denmark between 1980 and 2002, as well as two public registries that keep track of infectious diseases. They compared those records with records of children referred to psychiatric wards and later diagnosed with an autism spectrum disorder.
Of those children, almost 7400 were diagnosed with an autism spectrum disorder. The enquiry found that children who were admitted to the polyclinic for an communicable disease, either bacterial or viral, were more likely to receive a diagnosis of autism spectrum disorder. However, children admitted to the convalescent home for non-infectious diseases were also more likely to be diagnosed with autism than kids who were never hospitalized, the retreat found.
And the researchers could point to no particular infection that upped the risk. They therefore conclude that boyhood infections cannot be considered a cause of autism. "We find the same relationship between hospitalization due to many different infections and autism," celebrated lead study author Dr Hjordis Osk Atladottir, of the departments of epidemiology and biostatistics at the Institute of Public Health, University of Aarhus in Denmark. "If there were a causal relationship, it should be distribute for precise infections and not provide such an overall pattern of association".
The study was published in the May originate of the Archives of Pediatrics & Adolescent Medicine. Autism is a neurodevelopmental disorder that is characterized by problems with collective interaction, verbal and nonverbal communication, and restricted interests and behaviors. The control of autism seems to be rising, with an estimated 1 in 110 children affected by the disorder, according to the US Centers for Disease Control and Prevention.
Despite significant effort, the causes of autism be left unclear, although it's believed both genetic and environmental factors contribute, said Dr Andrew Zimmerman, kingpin of medical delving at the Center for Autism and Related Disorders at Kennedy Krieger Institute in Baltimore. Previous experimentation has suggested that children with autism are more likely to have immune system abnormalities, matchless some to theorize that autism might be triggered by infections.
Infections during beginning or girlhood do not seem to raise the risk of autism, new research finds. Researchers analyzed start records for the 1,4 million children born in Denmark between 1980 and 2002, as well as two public registries that keep track of infectious diseases. They compared those records with records of children referred to psychiatric wards and later diagnosed with an autism spectrum disorder.
Of those children, almost 7400 were diagnosed with an autism spectrum disorder. The enquiry found that children who were admitted to the polyclinic for an communicable disease, either bacterial or viral, were more likely to receive a diagnosis of autism spectrum disorder. However, children admitted to the convalescent home for non-infectious diseases were also more likely to be diagnosed with autism than kids who were never hospitalized, the retreat found.
And the researchers could point to no particular infection that upped the risk. They therefore conclude that boyhood infections cannot be considered a cause of autism. "We find the same relationship between hospitalization due to many different infections and autism," celebrated lead study author Dr Hjordis Osk Atladottir, of the departments of epidemiology and biostatistics at the Institute of Public Health, University of Aarhus in Denmark. "If there were a causal relationship, it should be distribute for precise infections and not provide such an overall pattern of association".
The study was published in the May originate of the Archives of Pediatrics & Adolescent Medicine. Autism is a neurodevelopmental disorder that is characterized by problems with collective interaction, verbal and nonverbal communication, and restricted interests and behaviors. The control of autism seems to be rising, with an estimated 1 in 110 children affected by the disorder, according to the US Centers for Disease Control and Prevention.
Despite significant effort, the causes of autism be left unclear, although it's believed both genetic and environmental factors contribute, said Dr Andrew Zimmerman, kingpin of medical delving at the Center for Autism and Related Disorders at Kennedy Krieger Institute in Baltimore. Previous experimentation has suggested that children with autism are more likely to have immune system abnormalities, matchless some to theorize that autism might be triggered by infections.
Wednesday 2 May 2018
Post Traumatic Stress Disorder Gives A Higher Risk Of Cardiovascular Disease
Post Traumatic Stress Disorder Gives A Higher Risk Of Cardiovascular Disease.
Veterans pain from post-traumatic emphasis on disorder, or PTSD, appear to be at higher endanger for heart disease. For the first time, researchers have linked PTSD with severe atherosclerosis (hardening of the arteries), as majestic by levels of calcium deposits in the arteries. The condition "is emerging as a significant jeopardize factor," said Dr Ramin Ebrahimi, co-principal investigator of a learning on the issue presented Wednesday at the annual meeting of the American Heart Association in Chicago. The authors are hoping that these and other, alike findings will prompt doctors, particularly primary punctiliousness physicians, to more carefully screen patients for PTSD and, if needed, follow up aggressively with screening and treatment.
Post-traumatic make a point of disorder - triggered by experiencing an event that causes intense fear, helplessness or awe - can include flashbacks, emotional numbing, overwhelming guilt and shame, being most startled, and difficulty maintaining close relationships. "When you go to a doctor, they ask questions about diabetes, boisterous blood pressure and cholesterol," said Ebrahimi, who is a research scientist at the Greater Los Angeles Veterans Administration Center. "The purpose would be for PTSD to become part of routine screening for mettle disease risk factors".
Although PTSD is commonly associated with war veterans, it's now also by many linked to people who have survived traumatic events, such as rape, a severe accident or an earthquake, saturate or other natural disaster. The authors reviewed electronic medical records of 286,194 veterans, most of them manful with an average age 63, who had been seen at Veterans Administration medical centers in southern California and Nevada. Some of the veterans had continue been on active duty as far back as the Korean War.
Researchers also had access to coronary artery calcium CT c con images for 637 of the patients, which showed that those with PTSD had more calcium built up in their arteries - a peril factor for heart disease - and more cases of atherosclerosis. About three-quarters of those diagnosed with PTSD had some calcium build-up, versus 59 percent of the veterans without the disorder. As a group, the veterans with PTSD had more unfeeling ailment of their arteries, with an average coronary artery calcification situation of 448, compared to a score of 332 in the veterans without PTSD - a significantly higher reading.
Veterans pain from post-traumatic emphasis on disorder, or PTSD, appear to be at higher endanger for heart disease. For the first time, researchers have linked PTSD with severe atherosclerosis (hardening of the arteries), as majestic by levels of calcium deposits in the arteries. The condition "is emerging as a significant jeopardize factor," said Dr Ramin Ebrahimi, co-principal investigator of a learning on the issue presented Wednesday at the annual meeting of the American Heart Association in Chicago. The authors are hoping that these and other, alike findings will prompt doctors, particularly primary punctiliousness physicians, to more carefully screen patients for PTSD and, if needed, follow up aggressively with screening and treatment.
Post-traumatic make a point of disorder - triggered by experiencing an event that causes intense fear, helplessness or awe - can include flashbacks, emotional numbing, overwhelming guilt and shame, being most startled, and difficulty maintaining close relationships. "When you go to a doctor, they ask questions about diabetes, boisterous blood pressure and cholesterol," said Ebrahimi, who is a research scientist at the Greater Los Angeles Veterans Administration Center. "The purpose would be for PTSD to become part of routine screening for mettle disease risk factors".
Although PTSD is commonly associated with war veterans, it's now also by many linked to people who have survived traumatic events, such as rape, a severe accident or an earthquake, saturate or other natural disaster. The authors reviewed electronic medical records of 286,194 veterans, most of them manful with an average age 63, who had been seen at Veterans Administration medical centers in southern California and Nevada. Some of the veterans had continue been on active duty as far back as the Korean War.
Researchers also had access to coronary artery calcium CT c con images for 637 of the patients, which showed that those with PTSD had more calcium built up in their arteries - a peril factor for heart disease - and more cases of atherosclerosis. About three-quarters of those diagnosed with PTSD had some calcium build-up, versus 59 percent of the veterans without the disorder. As a group, the veterans with PTSD had more unfeeling ailment of their arteries, with an average coronary artery calcification situation of 448, compared to a score of 332 in the veterans without PTSD - a significantly higher reading.
Thursday 28 January 2016
Diseases Of The Digestive Organs Is Increased In Children And Adolescents
Diseases Of The Digestive Organs Is Increased In Children And Adolescents.
Eating disorders have risen steadily in children and teens over the hold out few decades, with some of the sharpest increases occurring in boys and minority youths, according to a recent report. In one astonishing statistic cited in the report, an inquiry by the Agency for Healthcare Research and Quality found that hospitalizations for eating disorders jumped by 119 percent between 1999 and 2006 for younger than 12 kids. At the same age as despotic cases of anorexia and bulimia have risen, so too have "partial-syndrome" eating disorders - adolescent people who have some, but not all, of the symptoms of an eating disorder.
Athletes, including gymnasts and wrestlers, and performers, including dancers and models, may be only at risk, according to the report. "We are seeing a lot more eating disorders than we Euphemistic pre-owned to and we are seeing it in people we didn't associate with eating disorders in the past - a lot of boys, teeny kids, people of color and those with lower socioeconomic backgrounds," said surface author Dr David Rosen, a professor of pediatrics, internal medicine and psychiatry at University of Michigan. "The stereotype firm is of an affluent white girl of a certain age. We wanted proletariat to understand eating disorders are equal-opportunity disorders".
The report is published in the December go forth of Pediatrics. While an estimated 0,5 percent of adolescent girls in the United States have anorexia and about 1 to 2 percent have bulimia, experts viewpoint that between 0,8 to 14 percent of Americans approximately have at least some of the physical and psychological symptoms of an eating disorder, according to the report.
Boys now describe about 5 to 10 percent of those with eating disorders, although some research suggests that number may be even higher, said Lisa Lilenfeld, new president of the Eating Disorders Coalition for Research, Policy and Action in Washington, DC. Most studies that have been focused on mastery were based on patients in treatment centers, who tended to be milk-white females. "That does not represent all of those who are suffering. It's hard to say if eating disorders are on the ascent in males, or if we're just doing a better job of detecting it".
Rosen and his colleagues pored over more than 200 fresh studies on eating disorders. While much is unknown about what triggers these conditions, experts now read it takes more than media images of very thin women, although that's not to say those don't play a role.
Like other certifiable health problems and addictions, ranging from depression to anxiety disorder to alcoholism, descent and twin studies have shown that eating disorders can run in families, indicating there's a strong genetic component. "We second-hand to think eating disorders were the consequences of bad family dynamics, that the media caused eating disorders or that individuals who had destined personality traits got eating disorders. All of those can stage play a role, but it's just not that simple.
Eating disorders have risen steadily in children and teens over the hold out few decades, with some of the sharpest increases occurring in boys and minority youths, according to a recent report. In one astonishing statistic cited in the report, an inquiry by the Agency for Healthcare Research and Quality found that hospitalizations for eating disorders jumped by 119 percent between 1999 and 2006 for younger than 12 kids. At the same age as despotic cases of anorexia and bulimia have risen, so too have "partial-syndrome" eating disorders - adolescent people who have some, but not all, of the symptoms of an eating disorder.
Athletes, including gymnasts and wrestlers, and performers, including dancers and models, may be only at risk, according to the report. "We are seeing a lot more eating disorders than we Euphemistic pre-owned to and we are seeing it in people we didn't associate with eating disorders in the past - a lot of boys, teeny kids, people of color and those with lower socioeconomic backgrounds," said surface author Dr David Rosen, a professor of pediatrics, internal medicine and psychiatry at University of Michigan. "The stereotype firm is of an affluent white girl of a certain age. We wanted proletariat to understand eating disorders are equal-opportunity disorders".
The report is published in the December go forth of Pediatrics. While an estimated 0,5 percent of adolescent girls in the United States have anorexia and about 1 to 2 percent have bulimia, experts viewpoint that between 0,8 to 14 percent of Americans approximately have at least some of the physical and psychological symptoms of an eating disorder, according to the report.
Boys now describe about 5 to 10 percent of those with eating disorders, although some research suggests that number may be even higher, said Lisa Lilenfeld, new president of the Eating Disorders Coalition for Research, Policy and Action in Washington, DC. Most studies that have been focused on mastery were based on patients in treatment centers, who tended to be milk-white females. "That does not represent all of those who are suffering. It's hard to say if eating disorders are on the ascent in males, or if we're just doing a better job of detecting it".
Rosen and his colleagues pored over more than 200 fresh studies on eating disorders. While much is unknown about what triggers these conditions, experts now read it takes more than media images of very thin women, although that's not to say those don't play a role.
Like other certifiable health problems and addictions, ranging from depression to anxiety disorder to alcoholism, descent and twin studies have shown that eating disorders can run in families, indicating there's a strong genetic component. "We second-hand to think eating disorders were the consequences of bad family dynamics, that the media caused eating disorders or that individuals who had destined personality traits got eating disorders. All of those can stage play a role, but it's just not that simple.
Tuesday 17 December 2013
Relationship Between Immune System And Mental Illness
Relationship Between Immune System And Mental Illness.
In the chief controlled illustration of exactly how some psychiatric illnesses might be linked to an immune system gone awry, researchers boom they cured mice of an obsessive-compulsive condition known as "hair-pulling disorder" by tweaking the rodents' unaffected systems. Although scientists have noticed a link between the immune system and psychiatric illnesses, this is the leading evidence of a cause-and-effect relationship, said the authors of a study appearing in the May 28 conclusion of the journal Cell. The "cure" in this case was a bone marrow transplant, which replaced a incompetent gene with a normal one.
The excitement lies in the fact that this could open the way to new treatments for unusual mental disorders, although bone marrow transplants, which can be life-threatening in themselves, are not a likely candidate, at least not at this point. "There are some drugs already existing that are functional with respect to immune disorders," said haunt senior author Mario Capecchi, the recipient of a 2007 Nobel Prize in physiology or medicine. "This is very renewed information in terms of there being some kind of immune reaction in the body that could be contributing to mental vigour symptoms," said Jacqueline Phillips-Sabol, an assistant professor of neurosurgery and psychiatry at Texas A&M Health Science Center College of Medicine and top dog of the neuropsychology division at Scott & White in Temple, Texas. "This helps us persevere to unravel the mystery of mental illness, which reach-me-down to be shrouded in mysticism. We didn't know where it came from or what caused it".
However, Phillips-Sabol was sharp to point out that bone marrow transplants are not a reasonable treatment for mental health disorders. "That's likely a stretch at least at this point," she said. "Most patients who have obsessive-compulsive disorder (OCD) are utterly successfully treated with psychotherapy". "The story starts with a mouse mutant that has a very unusual behavior, which is very almost identical to the obsessive-compulsive spectrum disorder in humans called trichotillomania, when patients compulsively assassinate all their body hair," explained Capecchi, who is a distinguished professor of human genetics and biology at the University of Utah School of Medicine and an investigator with the Howard Hughes Medical Institute.
Some 2 percent to 3 percent of men and women worldwide go down from the disorder, he said. The same group of researchers had earlier discovered the ground for the odd behavior: these mice had changes in a gene known as Hoxb8. To their great surprise, the gene turns out to be confused in the development of microglia, a type of immune cell found in the perspicacity but originating in the bone marrow, whose known function is to clean up damage in the brain.
In the chief controlled illustration of exactly how some psychiatric illnesses might be linked to an immune system gone awry, researchers boom they cured mice of an obsessive-compulsive condition known as "hair-pulling disorder" by tweaking the rodents' unaffected systems. Although scientists have noticed a link between the immune system and psychiatric illnesses, this is the leading evidence of a cause-and-effect relationship, said the authors of a study appearing in the May 28 conclusion of the journal Cell. The "cure" in this case was a bone marrow transplant, which replaced a incompetent gene with a normal one.
The excitement lies in the fact that this could open the way to new treatments for unusual mental disorders, although bone marrow transplants, which can be life-threatening in themselves, are not a likely candidate, at least not at this point. "There are some drugs already existing that are functional with respect to immune disorders," said haunt senior author Mario Capecchi, the recipient of a 2007 Nobel Prize in physiology or medicine. "This is very renewed information in terms of there being some kind of immune reaction in the body that could be contributing to mental vigour symptoms," said Jacqueline Phillips-Sabol, an assistant professor of neurosurgery and psychiatry at Texas A&M Health Science Center College of Medicine and top dog of the neuropsychology division at Scott & White in Temple, Texas. "This helps us persevere to unravel the mystery of mental illness, which reach-me-down to be shrouded in mysticism. We didn't know where it came from or what caused it".
However, Phillips-Sabol was sharp to point out that bone marrow transplants are not a reasonable treatment for mental health disorders. "That's likely a stretch at least at this point," she said. "Most patients who have obsessive-compulsive disorder (OCD) are utterly successfully treated with psychotherapy". "The story starts with a mouse mutant that has a very unusual behavior, which is very almost identical to the obsessive-compulsive spectrum disorder in humans called trichotillomania, when patients compulsively assassinate all their body hair," explained Capecchi, who is a distinguished professor of human genetics and biology at the University of Utah School of Medicine and an investigator with the Howard Hughes Medical Institute.
Some 2 percent to 3 percent of men and women worldwide go down from the disorder, he said. The same group of researchers had earlier discovered the ground for the odd behavior: these mice had changes in a gene known as Hoxb8. To their great surprise, the gene turns out to be confused in the development of microglia, a type of immune cell found in the perspicacity but originating in the bone marrow, whose known function is to clean up damage in the brain.
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