Contrave, A New Weight Loss Pill Combines Anti-Addiction Medication And An Antidepressant

Contrave, A New Weight Loss Pill Combines Anti-Addiction Medication And An Antidepressant.
An pro admonitory panel recommended on Tuesday that Contrave, a supplementary weight-loss pill that combines an antidepressant with an anti-addiction medication, be approved by the US Food and Drug Administration. The 13-7 come out in favor of Contrave came amid agency concerns that the knock out might raise blood pressure in some patients and increase the risk of heart attacks and strokes mid some users, according to the Associated Press. But panelists voted 11-8 earlier in the daylight that those potential health risks could be studied after Contrave was approved.

The FDA does not have to follow the advice of its advisory committees, but it typically does. The activity is expected to make a decision on Contrave by Jan 31, 2011, the wire usefulness reported. Contrave is manufactured by Orexigen Therapeutics Inc. In October, the FDA voted against approving two other weight-loss drugs, Arena Pharmaceuticals' lorcaserin and Vivus' Qnexa, because of safeness concerns, according to the AP. Last July, a survey funded by Orexigen and published in The Lancet found that Contrave helped users abandon pounds when taken along with a beneficial diet and exercise.

People who took the drug for more than a year lost an average of 5 percent or more of body weight, depending on the quantity used, the team said. However, the regimen did come with side effects, and about half of think over participants dropped out before completing a year of treatment. Contrave is combination of two famous drugs, naltrexone (Revia, used to fight addictions) and the antidepressant bupropion (known by a few of names, including Wellbutrin).

The drug appears to boost weight loss by changing the workings of the body's medial nervous system, the researchers said. The study enrolled men (15 percent) and women (85 percent) from around the country, ranging in grow old from 18 to 65. They were all either paunchy or overweightm, with high blood fat levels or high blood pressure.

Experimental Diet Pill Contrave Brought A Small Weight Loss

Experimental Diet Pill Contrave Brought A Small Weight Loss.
Contrave, an theoretical bias loss drug that combines an antidepressant with an anti-addiction medication, appears to inform users shed pounds when taken along with a healthy diet and exercise, researchers report. People who took the stupefy for more than a year lost an average of 5 percent or more of body weight, depending on the quantity used, the team said. However, the regimen did come with side effects, and about half of scrutinize participants dropped out before completing a year of treatment.

Contrave is combination of two well-known drugs, naltrexone (Revia, in use to fight addictions) and the antidepressant bupropion (known by a number of names, including Wellbutrin). The drug, which is up for US Food and Drug Administration evaluate this December, appears to promote weight loss by changing the workings of the body's central nervous system, the researchers report.

The researchers, who divulge their findings online July 29, 2010 in The Lancet, enrolled men (15 percent) and women (85 percent) from around the country, ranging in length of existence from 18 to 65. They were all either heavy or overweight with high blood fat levels or merry blood pressure. The participants were told to eat less and exercise, and they were randomly assigned to wolf a twice-daily placebo or a combination of the two drugs with naltrexone at one of two levels.