Rheumatoid Arthritis And Shingles.
The newest medications in use to study autoimmune diseases such as rheumatoid arthritis don't appear to raise the risk of developing shingles, unusual research indicates. There has been concern that these medications, called anti-tumor necrosis factor (anti-TNF) drugs, might expansion the chances of a shingles infection (also known as herpes zoster) because they peg away by suppressing a part of the immune system that causes the autoimmune attack. "These are commonly hand-me-down drugs for people with rheumatoid arthritis and other autoimmune diseases, and the issue was whether or not they increased the risk of shingles.
We found there is no increased danger when using these drugs, which was reassuring," said study author Dr Kevin Winthrop, companion professor of infectious disease and public health and preventive medicine at Oregon Health and Science University in Portland. Results of the turn over are published in the March 6 issue of the Journal of the American Medical Association.
Shingles is a noteworthy concern for people with autoimmune conditions, particularly proletariat who are older and more at risk for developing shingles in general. Shingles is caused when the same virus that causes chickenpox is reactivated. The symptoms of shingles, however, are often far more moment than chickenpox. It typically starts with a violent or tingling pain, which is followed by the appearance of fluid-filled blisters, according to the US National Institutes of Neurological Disorders and Stroke.
Shingles smarting can vary from mild to so severe that even the lightest touch causes earnest pain. People who have rheumatoid arthritis already have an increased risk of shingles, although Winthrop said it's not verbatim clear why. It may be due to older age, or it may have something to do with the disease itself. Rheumatoid arthritis and other autoimmune conditions are treated with many rare medications that help dampen the immune methodology and, hopefully, the autoimmune attack.
Showing posts with label shingles. Show all posts
Showing posts with label shingles. Show all posts
Monday 25 February 2019
Wednesday 31 October 2018
New Studies Of Treatment Of Herpes Zoster
New Studies Of Treatment Of Herpes Zoster.
The sway of a irritating condition known as shingles is increasing in the United States, but new research says the chickenpox vaccine isn't to blame. Shingles is caused by the same virus that causes chickenpox, the varicella zoster virus. Researchers have theorized that widespread chickenpox vaccination since the 1990s might have given shingles an unintended boost. But that theory didn't pit out in a survey of nearly 3 million older adults.
And "The chickenpox vaccine program was introduced in 1996, so we looked at the rate of shingles from the primordial '90s to 2010, and found that shingles was already increasing before the vaccine program started," said inspect creator Dr Craig Hales, a medical epidemiologist at the US Centers for Disease Control and Prevention. "And as immunization coverage in children reached 90 percent, shingles continued at the same rate". Once someone has had chickenpox, the varicella zoster virus stays in the body.
It lies unmoving for years, often even for decades, but then something happens to reactivate it. When it's reactivated, it's called herpes zoster or shingles. Exposure to children with chickenpox boosts adults' absolution to the virus. But experts wondered if vaccinating a entire formulation of children against chickenpox might agitate the class of shingles in older people, who have already been exposed to the chickenpox virus.
And "Our immunity plainly wanes over time, and once it wanes enough, that's when the virus can reactivate. So, if we're never exposed to children with chickenpox, would we capitulate that normal immunity boost?" To answer this question, Hales and his colleagues reviewed Medicare claims observations from 1992 to 2010 that included about 2,8 million commoners over the age of 65. They found that annual rates of shingles increased 39 percent over the 18-year retreat period.
However, they didn't find a statistically significant change in the rate after the introduction of the chickenpox vaccine. They also found that the be worthy of of shingles didn't vary from state to state where there were different rates of chickenpox vaccine coverage. These findings, published in the Dec 3, 2013 stream of the Annals of Internal Medicine, suggest the chickenpox vaccine isn't affiliate to the increase in shingles, according to Hales.
The sway of a irritating condition known as shingles is increasing in the United States, but new research says the chickenpox vaccine isn't to blame. Shingles is caused by the same virus that causes chickenpox, the varicella zoster virus. Researchers have theorized that widespread chickenpox vaccination since the 1990s might have given shingles an unintended boost. But that theory didn't pit out in a survey of nearly 3 million older adults.
And "The chickenpox vaccine program was introduced in 1996, so we looked at the rate of shingles from the primordial '90s to 2010, and found that shingles was already increasing before the vaccine program started," said inspect creator Dr Craig Hales, a medical epidemiologist at the US Centers for Disease Control and Prevention. "And as immunization coverage in children reached 90 percent, shingles continued at the same rate". Once someone has had chickenpox, the varicella zoster virus stays in the body.
It lies unmoving for years, often even for decades, but then something happens to reactivate it. When it's reactivated, it's called herpes zoster or shingles. Exposure to children with chickenpox boosts adults' absolution to the virus. But experts wondered if vaccinating a entire formulation of children against chickenpox might agitate the class of shingles in older people, who have already been exposed to the chickenpox virus.
And "Our immunity plainly wanes over time, and once it wanes enough, that's when the virus can reactivate. So, if we're never exposed to children with chickenpox, would we capitulate that normal immunity boost?" To answer this question, Hales and his colleagues reviewed Medicare claims observations from 1992 to 2010 that included about 2,8 million commoners over the age of 65. They found that annual rates of shingles increased 39 percent over the 18-year retreat period.
However, they didn't find a statistically significant change in the rate after the introduction of the chickenpox vaccine. They also found that the be worthy of of shingles didn't vary from state to state where there were different rates of chickenpox vaccine coverage. These findings, published in the Dec 3, 2013 stream of the Annals of Internal Medicine, suggest the chickenpox vaccine isn't affiliate to the increase in shingles, according to Hales.
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