A Promising Way To Treat Specific Lymphoma.
Researchers have identified a gene deviant that may proposition a target for new treatments for a type of lymphoma. The pair found that a mutation of the MYD88 gene is one of the most frequent genetic abnormalities in patients with this cancer, known as massive B cell lymphoma. The MYD88 gene encodes a protein that is crucial for healthy immune response to invading microorganisms.
The mutation identified in this study can cause uncontrolled cellular signaling, resulting in the survival of pernicious cells. A subgroup of the large B cell lymphoma that has a dismally enervated cure rate - known as the activated B cell-like (ABC) subtype - appears exceptionally susceptible to the gene.