The Depression Is Associated With Heart Troubles

The Depression Is Associated With Heart Troubles.
Depression is more low-grade in patients who undergo heart bypass surgery, and a new study finds that short-term use of antidepressants may scholarship patients' recovery May 2013. "Depression among patients requiring or having undergone evade surgery is high and can significantly impact postoperative recovery," said one crackerjack not connected to the study, Dr Bryan Bruno, acting chairman of the department of psychiatry at Lenox Hill Hospital in New York City. In this study, a line-up of French researchers looked at 182 patients who started charming a selective serotonin reuptake inhibitor (SSRI) antidepressant two to three weeks before undergoing coronary artery ignore graft surgery and continued delightful it for six months after the procedure.

SSRIs include widely used antidepressants such as Celexa, Lexapro, Prozac, Paxil and Zoloft. In this study, patients took one 10 milligram lozenge of Lexapro (escitalopram) daily. The office was funded by Lexapro's maker, H Lundbeck A/S. The outcomes of patients prescribed Lexapro were compared to 179 patients who took an supine placebo as an alternative of the antidepressant.

During the six months after the surgery, the patients who took the antidepressant reported less glumness and better quality of life than those who took the placebo, the researchers reported. In addition, attractive antidepressants did not increase the risk of complications or death in the year after surgery, according to the study, which appears in the May question of the Annals of Thoracic Surgery.

The study suggests that taking the antidepressant "enables patients who were at least somewhat depressed before surgery for coronary artery disease to give the impression better more quickly after surgery, without influencing the complication rate," study leader Dr Sidney Chocron said in a weekly news release. "Even slight depression before coronary surgery can retard a patient's mental recovery and increase the feeling of pain after surgery," added Chocron, a professor of cardiac surgery at University Hospital Jean Minjoz in Besancon.

Prescribing antidepressants for patients before they have nub alternate way surgery helps them "get on with their lives more quickly after such a serious surgical procedure," Chocron said in the story release. Bruno agreed that treating even mild depression is important. "I concede with the authors' concluding suggestion that, unless contraindicated, there should be a relatively low edge - for initiating antidepressant therapy" in these types of heart patients, he said. But another pundit said the study reveals little about the strategy for patients with more severe depression.

So "The forgiving benefit associated with the use of antidepressants in this study is consistent with a population which was not significantly depressed," noted Dr Dan Iosifescu, headman of the Mood and Anxiety Disorders Program and associate professor of psychiatry and neuroscience at Mount Sinai School of Medicine in New York City. He said "the patients in this bookwork had depressive symptoms in a line up which usually does not qualify for a diagnosis of depression" acdarmin gel price. Therefore, "on control this study provides helpful information on the safety of antidepressants in post- go patients," Iosifescu said, "but does not contribute to our understanding of their usefulness since the study population appears to have very depressed rates of depression".