Scanning The Human Genome Provide Insights Into The Likelihood Of Future Disease

Scanning The Human Genome Provide Insights Into The Likelihood Of Future Disease.
Stephen Quake, a Stanford University professor of bioengineering, now has a very great intelligence of his own genetic destiny. Quake's DNA was the heart of the first completely mapped genome of a salutary person aimed at predicting future health risks. The read over was conducted by a team of Stanford researchers and cost about $50,000. The researchers say they can now intimate Quake's risk for dozens of diseases and how he might respond to a number of widely used medicines.

This strain of individualized risk report could become common within the next decade and may become much cheaper, according to the Stanford team. "The $1000 genome trial is coming fast. The challenge lies in knowing what to do with all that information. We've focused on establishing priorities that will be most practical when a patient and a physician are sitting together looking at the computer screen," Euan Ashley, an subordinate professor of medicine, said in a university news release.

Those priorities subsume assessing how a person's activity levels, weight, diet and other lifestyle habits ally with his or her genetic risk for, or protection against, health problems such as diabetes or sincerity attack. It's also important to determine if a certain medication is likely to benefit the patient or cause dangerous side effects.

"We're at the dawn of a new age in genomics. Information like this will enable doctors to yield personalized health care like never before. Patients at risk for certain diseases will be able to gain closer monitoring and more frequent testing, while those who are at lower risk will be spared unnecessary tests. This will have signal economic benefits as well, because it improves the efficiency of medicine".

In mapping Quake's genome, researchers designed an algorithm that overlaid his genetic data, on outstrip of what was already known about his robustness risks based on his age and gender. The analysis focused on 55 conditions, ranging from diabetes and corpulence to gum disease and schizophrenia.

The analysis revealed that Quake has a 23 percent gamble of prostate cancer and a 1,4 percent risk of Alzheimer's disease. He also has a more than 50 percent imperil of developing obesity, type 2 diabetes and coronary artery disease. However, lifestyle habits can have a balanced impact on genetic risk factors, the experts noted.

Speaking to the Associated Press, Quake said that a bosom genome reading might not be a great idea for everyone. "All you understand about when they talk about your genome is ways you're going to die and get sick. It doesn't express you you're going to be happy or a great athlete. If you're a worrier, this is not for you".

And another masterly unconnected to the research worried about privacy issues. "The genie is now out of the bottle," Nilesh Samani, of the concern of cardiovascular sciences at the University of Leicester, told the AP. "We need to characterize carefully about whether we need laws to prevent genetic information from getting into the wrong hands".

The research was funded by the US National Institute of General Medical Sciences, and the National Heart, Lung and Blood Institute, among others. All the researchers have either pecuniary ties to, or are involved with, genetic testing firms, medication makers or other health industry companies curatio androanagen side effects. The analyse was released online April 29 and will be published in the May 1 print issue of The Lancet.