Alzheimer's Disease Is Associated With A High Blood Pressure

Alzheimer's Disease Is Associated With A High Blood Pressure.
People distress from cardiovascular infirmity who have lower-than-normal blood pressure may face a higher gamble of brain atrophy - the death of brain cells or connections between brain cells, Dutch researchers account June 2013. Such brain atrophy can lead to Alzheimer's infection or dementia in these patients. In contrast, similar patients with high blood pressure can uninteresting brain atrophy by lowering their blood pressure, the researchers added.

Blood pressure is measured using two readings. The choicest number, called systolic pressure, gauges the pressure of blood in motion through arteries. The bottom number, called diastolic pressure, measures the pressure in the arteries between heartbeats. Normal blood persuade for adults is less than 120/80, according to the US National Heart, Lung, and Blood Institute.

For the study, 70 to 90 was considered orthodox diastolic blood pressure, while under 70 was considered low. "Our observations might suggest that patients with cardiovascular disease represent a subgroup within the catholic population in whom low diastolic blood pressure might be harmful," said researcher Dr Majon Muller, an epidemiologist and geriatrician at VU University Medical Center in Amsterdam.

On the other hand, lowering blood demand in clan with high blood pressure might slow brain atrophy. "Our findings could connote that blood pressure lowering is beneficial in patients with higher blood squeezing levels, but one should be cautious with further blood pressure lowering in patients who already have low diastolic blood pressure".

The statement was published in the June 10 online edition of JAMA Neurology. A US wonderful noted the complex effects of blood pressure levels on the brain. "High blood put the screws on has been shown to increase the risk of vascular brain lesions and brain atrophy. Trials of blood insistence lowering in patients with hypertension have shown reduced risk of brain lesions," said Dr Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association.

However, in patients with hypertension, the relation between the levels of systolic and diastolic blood intimidation and wisdom atrophy has been less clear. This new study suggests that low diastolic blood bring pressure to bear levels were associated with brain atrophy regardless of blood pressure levels after patients developed dementia. "These findings suggest that while healing and control of high blood coercion is very important for brain and cardiovascular health, caution is needed in patients who have low diastolic blood compel levels".

To see what changes blood pressure would make in the progression of brain atrophy, Muller's grouping studied 663 patients who suffered from heart disease, cardiovascular disease, beside the point artery disease or abdominal aortic aneurysm. The average age of participants was 57 and most were men. People whose diastolic blood pressing was below 70 had more brain atrophy over time, the read found.

For people with higher-than-normal blood pressure, brain atrophy decreased when their blood tension did. When blood pressure rose, however, atrophy increased. Another expert, Dr Sam Gandy, fellow-worker director of the Mount Sinai Alzheimer's Disease Research Center in New York City, said that the decree "is an important cautionary tale".

This implies that one must alter the approach to the individual patient. Correction of hypertension is helpful, but reducing blood constraint in patients with normal blood pressure is risky and complicated" albenza for giardia. Although the swat found an association between low diastolic blood pressure and the risk of developing brain atrophy for nation with artery disease, it did not establish a cause-and-effect relationship.