Cryoneedles A Possible Alternative To Botox In Fighting Against Wrinkles.
A rejuvenated technology that time zaps away forehead wrinkles by freezing the nerves shows bid fair in early clinical trials, researchers say. The technique, if in approved by the US Food and Drug Administration, could provide an alternative to Botox and Dysport. Both are injectable forms of Botulinum toxin breed A, a neurotoxin that, when injected in tight quantities, temporarily paralyzes facial muscles, thereby reducing wrinkles. "It's a toxin-free option to treating unwanted lines and wrinkles, similar to what is being done with Botox and Dysport," said inquiry co-author Francis Palmer, director of facial plastic surgery at the University of Southern California School of Medicine in Los Angeles.
And "From the untimely clinical trials, this procedure - which its maker calls cryoneuromodulation - appears to have the same clinical efficacy and refuge comparable to the existing techniques". Palmer is also consulting medical governor of MyoScience Inc, the Redwood City (California) - based attendance developing the cryotechnology. The results of the clinical trials were to be presented Friday at an American Society for Laser Medicine and Surgery (ASLMS) discussion in Grapevine, Texas.
To do the procedure, physicians use modest needles - "cryoprobes" - to deliver cold to nerves race through the forehead, specifically the temporal branch of the frontal nerve. The cold freezes the nerve, which interrupts the spirit signal and relaxes the muscle that causes vertical and horizontal forehead lines. Although the audacity quickly returns to normal body temperature, the cold temporarily "injures" the nerve, allowing the special to remain interrupted for some period of time after the patient leaves the office.
The system does not permanently damage the nerve. Researchers said they are still refining the technique and could not say how elongate the effect lasts, but it seems to be comparable to Botox, which works for about three to four months. Physicians would be in want of training to identify the nerve that should be targeted.
The 15-minute treatment is done using local anesthesia, according to the researchers. The reported study only looks at forehead wrinkles; future research will study the conduct elsewhere on the face. For the study, researchers tried the technique on 31 people, all of whom had fewer wrinkles after two to eight injections. The most run-of-the-mill side effects were headaches and crust redness.
The level of discomfort was comparable to that from Botox or fillers. But unlike Botox, which takes a few days to punt in, the effects of the cryotechnology are seen immediately, the researchers say. Because this swat was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.
Palmer said he didn't contemplate the new technology as a replacement for Botox, but instead as an alternative for kin who don't want an injection of a neurotoxin. The company will eventually seek FDA approval as a medical device. Palmer said the flock might first seek approval in Europe.
Dr Brian Zelickson, an affiliate professor of dermatology at the University of Minnesota in Minneapolis, said the technique sounds promising, but needs more analyse to determine how long results last and to make sure no lasting sand or muscle injury occurs that could cause permanent changes in sensation. He agreed that the toxin-free cosmetic strategy might win some followers.
So "Botox and Dysport are very easy, very quick, the patient satisfaction outline is great and there are very few side effects," said Zelickson, incoming president of ASLMS. "It's a high lounge to leap over, but there are some people that don't like the concept of injecting Botulinum toxin into their bodies. If there were a action that could be done, that doesn't inject any chemical into the system and could yield the same results for the same duration, there is a buy and sell for that" problem solutions. According to the American Society for Aesthetic Plastic Surgery, Botox and Dysport injections surmount their list of nonsurgical procedures.
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