Body Weight Affects Kidney Disease

Body Weight Affects Kidney Disease.
Obesity increases the chance of developing kidney disease, a unexplored study suggests. Moreover, declines in kidney function can be detected large before people develop other obesity-related diseases such as diabetes and high blood pressure, the researchers said in Dec, 2013. The researchers analyzed statistics collected from nearly 3000 wrathful and white young adults who had normal kidney function. The participants, who had an average period of 35, were grouped according to four ranges of body-mass index (BMI), a measurement of body fat based on altitude and weight.

The groups were normal weight, overweight, obese and extremely obese. Over time, kidney business decreased in all the participants, but the decline was much greater and quicker in overweight and heavy people, and appeared to be linked solely with body-mass index. "When we accounted for diabetes, merry blood pressure and inflammatory processes, body-mass index was still a predictor of kidney function decline," lucubrate first author Dr Vanessa Grubbs, an assistant adjunct professor of c physic at the University of California, San Francisco, said in a university news release.

So "There was something single about just being too large that in and of itself affected kidney function even before the onset of kidney disease. "We're not able to needle out the reason for that just yet, but we're hoping to look at it in a future study". The researchers also found that measuring blood levels of a protein called cystatin C is better than the more low-grade method of measuring creatinine levels in detecting hidden changes in kidney function.

This holds true even when kidney changes are still within what is considered the run-of-the-mill range. "The fact that we were able to use this marker to see declines in kidney ceremony long before patients would be deemed to have chronic kidney disease is good, in that it may allow us to detect problems earlier and expectantly intervene sooner. The findings, published online recently in the American Journal of Kidney Diseases, show the necessity for doctors to intervene early to prevent kidney illness in obese patients, the researchers said.

And "We're getting larger and larger at younger and younger ages, so the problems we will sight that are directly related to obesity are going to become more common, and they're going to kick-off earlier in life. "Even before the level at which we can diagnose illnesses, decline in kidney function is happening. Is it reversible? We're not sure. Preventable? It stands to pretext that it would be before and after lotrisone. Although the reflect on showed an association between obesity and increased risk of kidney disease, it did not prove a cause-and-effect relationship.