How To Transfer One Or More Embryos Using IVF

How To Transfer One Or More Embryos Using IVF.
Women who weather in-vitro fertilization (IVF) are almost five times more fitting to give birth to a unwed healthy baby following the implantation of a single embryo than are women who choose to have two embryos implanted at the same time, an universal team of experts has found. The finding comes from an analysis of details involving nearly 1400 women who participated in one of eight different embryo transfer studies. Approximately half of the women underwent procedures involving the unmarried transfer of an embryo, while the other half underwent a dual embryo procedure.

Overall, the study authors noted that, relative to a double embryo transfer, a sole embryo transfer appears to significantly increase the chances of carrying a baby to a intense term of more than 37 weeks. In addition to lowering the risk for premature birth, a unique embryo transfer also appeared to lower the risk for delivering a low birth weight baby, DJ McLernon, a scrutiny fellow with the medical statistics team in the section of population healthfulness at the University of Aberdeen in the United Kingdom, and colleagues reported in the Dec 22 2010 online issue of BMJ.

"Our review should be useful in informing decision making regarding the number of embryos to hand in IVF," the authors wrote in their report. They added that their observations could offer hands-on guidance to would-be mothers and doctors who are eager to foster optimal conditions for a successful pregnancy, while at the same adjust hoping to avoid the increased health risks associated with IVF procedures that give take place to multiple-birth pregnancies.

The authors concluded that doctors should advise patients to choose the single embryo transport option over what appears to be the less optimal double embryo transfer option.

At face value, the information seemed to suggest that the double embryo transfer option does, in fact, offer the materfamilias much better odds for giving birth to a single healthy baby. While among study participants just 27 percent of distinct embryo transfer procedures resulted in the birth of a healthy baby, that reckon rose to 42 percent of double embryo transfer births, the investigators found.

However, that varnish was narrowed considerably when the authors focused on those women undergoing an initial single embryo remove procedure who then underwent a second single implant (of a frozen embryo). That script (in which, in essence, two single embryo transfers are conducted in sequence) prompted a 38 percent good rate - a figure just 4 percent shy of the 42 percent good fortune rate attributed to two embryos being implanted simultaneously.

What's more, the researchers further found that a isolated embryo transfer offered women an 87 percent better chance of carrying a babe in arms to full-term than a double embryo transfer.

In addition, the single embryo transfer entailed just one-third of the imperil (compared with the double embryo transfer procedure) that the mother would ultimately deliver a dirty birth weight baby.

Commenting on the study, Dr Laurel Stadtmauer, an associate professor of obstetrics and gynecology and IVF colleague director of the Eastern Virginia Medical School Jones Institute for Reproductive Medicine in Norfolk, Va., described the in circulation effort as "very convincing".

"There is a consensus that there is a maximum number of multiple births from IVF, and we're all doing everything we can to reduce that rate of delivery because we know that premature birth and multiple births do lead to a higher risk for the babies and for the mother".

"And this certainly shows that cumulatively you can often effect a much better outcome with two separate single embryo transfers compared with one overlapped embryo transfer - which would mean a much lower chance of a multiple pregnancy and all the kindred complications," Stadtmauer continued.

"However, while a single embryo transfer is appropriate for a number of women it's not becoming in all women. Because while in young women or women with good prognostic factors a singular embryo transfer can be very successful, in women over the age of 38 or women with low chances of pregnancy and in want prognostic factors, there would be a significant reduction in success compared to a double pregnancy transfer," she cautioned.

"There are also pecuniary and emotional costs to undergoing a procedure twice, particularly as there is always a risk for failure. So not all women are handily convinced to choose the single transfer option. So while it's finally the future, it's not for everybody website. But the better we get at selecting which embryos have the highest chances of implanting, the better we can get at directing patients promoting elective single embryo transfers".