Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat

Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat.
Stem cells charmed from the belly fleshiness of 10 centre attack patients managed to improve several measures of heart function, Dutch researchers report. This is the win time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual rendezvous in Chicago. But the improvements, though to some degree dramatic in this small group of patients, were not statistically significant, probably due to the fixed number of participants in the study.

And another expert urged caution when interpreting the results. "The style issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, armchair of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City. This deliberate over only looked at "surrogates," sense measures of heart function that might predict better future health in the patient.

So "This cannot be interpreted as if they presently represent positive clinical outcomes. These certainly are rosy stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".

Another caveat: All the patients in this go were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not surely to people who aren't white. Fat tissue yields many more staunch cells than bone marrow (which has been studied before) and is much easier to access.

In bone marrow, 40 cubic centimeters (cc) typically consent about 25000 stem cells, which is "not nearly enough to treat woman in the street with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to run with, those retard cells would have to be cultured, a process that can take six to eight weeks.

By contrast, 100 cc's of well-fed tissue yield millions of stem cells, plenty to stir with. A hundred cc's is about the size of a coffee cup - a European coffee cup, not the mega-size of American coffee containers, Duckers emphasized. "With that many cells, you can send to Coventry them and give them to the steadfast right away as they come into the hospital".

All patients in this double-blind, placebo-controlled study (11 men and three women) arrived at the sanitarium having suffered a severe heart attack. All then underwent cardiac catheterization to assess blood flow, followed by percutaneous coronary intervention (PCI), more commonly known as angioplasty, to rekindle blood flow.

Within 24 hours of the quintessence attack, doctors performed liposuction to carry away fat tissue, isolated 20 million stem cells and gave them back to the patients through a catheter. The infusion took no more than 10 minutes. Ten patients received prow cells and four received a placebo infusion. "It was done very, very quickly, all in the same day".

Six months after the procedure, check chamber patients had better blood flow (more than triple the compute compared to patients getting a placebo), a 5,7 percent increase in heart pumping ability, and a 50 percent reduction in scarring of understanding muscle (from 31,6 percent right after the core attack to 15,4 percent). Placebo patients saw no decrease in scarring.

And "In theory the use of stock cells to improve myocardial perfusion blood flow and cardiac performance is very favourable - but to the present time, although many approaches to stem cell use have been tested, there really has not yet been evidence of a clinically profitable important result. That doesn't mean that stem cell research isn't an weighty lead to follow" view homepage. The Dutch research team is now embarking on a trial that will at enroll 375 heart attack patients at 35 medical centers in the European Union to further check stem cell infusions.